![]() Pickup quote states, " Bloody recharge".Jumper Cables, Grants an active item charge every 15 enemies killed.Headless Baby, Spawns a familiar that follows Isaac, leaving blood creep on the ground.Heals a Half Red Heart whenever Leech kills an enemy. Leech, Spawns a leech familiar that chases enemies, dealing ~3 damage per second.Pickup quote states, " Blood laser barrage".Brimstone, Replaces Isaac's tears with a charged laser.Anemia is a decrease in the blood's ability to carry oxygen.Anemic, after taking damage, grants a trail of red creep for the room.Sharp Straw, Damages all enemies in the room, has a chance to drop a half soul heart if an enemy is hit. ![]() Pickup quote states, "Portable blood bank.".IV Bag, drops Pennies at the cost of depleting half of a Red Heart container.The word blood appears in the pickup quote of the item. Pickup quote states, "Drips with blood.".Bloody Crown, Treasure Rooms now appear in chapter 4.Bloody Penny, when a coin is collected, grants a 50% chance to drop a half Red Heart.Bloody Gust, When Isaac takes damage, he gains speed and tears for the rest of the floor.After killing enough enemies, it becomes more powerful and drops red hearts after killing enemies, but will also try to hurt Isaac. Blood Puppy, Spawns a familiar that chases enemies.Increases damage and speed for the floor based on the amount drained. Blood Oath, Stabs Isaac at the beginning of each floor, draining his red hearts.Isaac can place bombs at the cost of half a heart if he doesn't have any. Blood Bombs, Bombs leave behind damaging red creep.Bloodshot Eye, Spawns an orbital familiar that deals 30 damage per second and fires a randomly angled tear every 2 seconds.Lusty Blood, increases damage by 0.5 up to 10 times in the current room each time a monster is defeated.Bloody Lust, after taking damage, grants increased damage for the floor.Blood of the Martyr, grants increased damage and turns Isaac's tears into blood tears.Blood Clot, grants increased damage and range.Blood Rights, damages entire room at the cost of depleting a full Red Heart container.The word "blood" appears in the title of the item. Blood Donation Machine, a machine which depletes half of a Red Heart container in exchange for dropping coins.Some things that aren't items that reference Blood Challenges īloody Mary: A Bethany challenge that starts with some blood related items
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